Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838913 | 0.94 | RAB9A (0.49) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9837558 | 0.93 | RAB9A (0.51) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9838818 | 0.81 | EPHX1 (0.41) | GAAEPHX1RAB9AHSD11B1EPHX2 | |
| SCHEMBL9838897 | 0.78 | EPHX1 (0.51) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9837559 | 0.77 | RAB9A (0.54) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9837856 | 0.76 | RAB9A (0.49) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9837842 | 0.75 | EPHX1 (0.51) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL9837550 | 0.75 | EPHX1 (0.48) | GAAEPHX1RAB9APDK1PDK2 | |
| SCHEMBL31488958 | 0.73 | LTA4H (0.42) | GAAEPHX1RAB9ALMNASSTR4 | |
| SCHEMBL9837845 | 0.72 | KIF11 (0.43) | PKMRAB9AEPHX2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | disclosed |
| EP-0276122-A2 | Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-27 | — | — | EP | disclosed |