SCHEMBL9839637

SCHEMBL9839637

CCC(=O)C1=CC2(C)CCC(C)(C)C2C1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11364049 0.57 CHRNB2 (0.33) CHRNB2CHRNA4
SCHEMBL11949184 0.56
SCHEMBL9839632 0.56 ALOX15 (0.31) ALOX15
SCHEMBL18415040 0.55 CHRNB2 (0.35) CHRNB2CHRNA4
SCHEMBL13776654 0.55
SCHEMBL11480809 0.55 CHRNB2 (0.41) ALDH1A1CYP3A4CHRNB2CHRNA4
SCHEMBL445095 0.54 CHRNB2 (0.37) CYP3A4CHRNB2CHRNA4
SCHEMBL2051779 0.54
SCHEMBL6907314 0.54
SCHEMBL10293946 0.53 CHRNB2 (0.36) CYP3A4CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260585-B1 BICYCLIC KETONES, METHOD FOR THEIR PRODUCTION AND AROMA AND/OR FLAVOUR COMPOSITIONS CONTAINING SAID KETONES L. GIVAUDAN & CIE Société Anonyme (CH) 1991-10-16 EP claimed
US-4877904-A Bicyclic ketones as odorants and flavorants GIVAUDAN CORPORATION (US) 1989-10-31 US claimed
EP-0260585-A2 Bicyclic ketones, method for their production and aroma and/or flavour compositions containing said ketones L. GIVAUDAN & CIE Société Anonyme (CH) 1988-03-23 EP claimed
EP-0260585-B1 BICYCLIC KETONES, METHOD FOR THEIR PRODUCTION AND AROMA AND/OR FLAVOUR COMPOSITIONS CONTAINING SAID KETONES L. GIVAUDAN & CIE Société Anonyme (CH) 1991-10-16 EP disclosed
US-4877904-A Bicyclic ketones as odorants and flavorants GIVAUDAN CORPORATION (US) 1989-10-31 US disclosed
EP-0260585-A2 Bicyclic ketones, method for their production and aroma and/or flavour compositions containing said ketones L. GIVAUDAN & CIE Société Anonyme (CH) 1988-03-23 EP disclosed