SCHEMBL5789486

SCHEMBL5789486

CCOC(=O)[C@@H](C)Oc1ccc(OC(C)=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
KMT2A Q03164 3/20 0.56
EPHX2 P34913 2/20 0.48
ELANE P08246 3/20 0.46
MAPT P10636 2/20 0.46
POLB P06746 2/20 0.43
PKM P14618 1/20 0.43
ALDH2 P05091 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5789487 1.00 LMNA (0.58) LMNAL3MBTL1KMT2AEPHX2ELANE
SCHEMBL9837990 0.86 ALDH1A1 (0.46) LMNAL3MBTL1KMT2AELANEMAPT
SCHEMBL11548487 0.84 L3MBTL1 (0.63) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL9063261 0.84 LMNA (0.63) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL9857703 0.84 LMNA (0.63) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL5205374 0.84 LMNA (0.63) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL18562096 0.84 LMNA (0.63) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL5789029 0.83 LMNA (0.58) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL5789027 0.83 LMNA (0.58) LMNAL3MBTL1KMT2AEPHX2MAPT
SCHEMBL5112826 0.83 LMNA (0.61) LMNAL3MBTL1KMT2AEPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006001562-A1 A PROCESS FOR OPTICAL PURE (R)-2-PHENOXYPROPIONIC ACID DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-01-05 WO disclosed