Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATF4 | P18848 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129676 | 0.82 | ALDH1A1 (0.37) | HPGDLMNAALDH1A1MMP13RAB9A | |
| SCHEMBL9839182 | 0.81 | ALDH1A1 (0.36) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL31608981 | 0.70 | MAP4K4 (0.44) | HPGDKDM4EALDH1A1ATF4MAPT | |
| SCHEMBL9804270 | 0.69 | SLC6A4 (0.44) | ALDH1A1WDR91 | |
| SCHEMBL16738423 | 0.68 | ADAMTS4 (0.36) | HPGDLMNAALDH1A1HTTMAPT | |
| SCHEMBL29045445 | 0.68 | MMP13 (0.34) | MMP13MEN1KMT2AMAOB | |
| SCHEMBL5944957 | 0.67 | MAOB (0.40) | LMNAATF4MAPTRAB9AUSP2 | |
| SCHEMBL18372576 | 0.66 | SLC6A3 (0.41) | ALDH1A1ATF4MMP13ABCB11MEN1 | |
| SCHEMBL17653823 | 0.65 | WDR91 (0.61) | WDR91MEN1KMT2AMAOB | |
| SCHEMBL3513070 | 0.64 | MAPT (0.34) | HTTMAPTUSP2MAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245792-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC-ACID ESTERS | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-5004569-A | Using phosphite containing oxetane groups as esterification catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |
| EP-0245792-A2 | Process for the preparation of carboxylic-acid esters | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| US-4225483-A | Boric acid esters and oxetanes for stabilizing phosphite-free polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0001823-A2 | Use of esters of boric acid to stabilize phosphite-free polycarbonates, and the obtained stabilized polycarbonate moulding compositions | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |