Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839761 | 0.93 | EGFR (0.42) | EGFRERBB2CYP2C9CYP2C19POLB | |
| SCHEMBL9839524 | 0.89 | CNR2 (0.45) | EGFRERBB2CNR2HSD17B3POLB | |
| SCHEMBL9838217 | 0.88 | CNR2 (0.43) | HDAC3HDAC1HDAC2CNR2CYP2C9 | |
| SCHEMBL9839770 | 0.82 | ALDH1A1 (0.54) | CYP2C9CYP2C19POLBMAPTALDH1A1 | |
| SCHEMBL9840321 | 0.81 | CNR2 (0.43) | EGFRERBB2CNR2MAPTALDH1A1 | |
| SCHEMBL9839756 | 0.76 | HSD11B1 (0.51) | HDAC3HDAC1HDAC2CNR2POLB | |
| SCHEMBL9839720 | 0.76 | EGFR (0.39) | EGFRERBB2HDAC3HDAC1HDAC2 | |
| SCHEMBL6565246 | 0.74 | EGFR (0.47) | EGFRERBB2CNR2 | |
| SCHEMBL9838463 | 0.74 | EGFR (0.46) | EGFRERBB2HDAC3HDAC1HDAC2 | |
| SCHEMBL9749957 | 0.73 | HDAC3 (0.40) | EGFRERBB2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057154-A | Colorfastness, stability | RICOH COMPANY, LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |