Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MYOC | Q99972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468592 | 0.98 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL8330156 | 0.92 | MEN1 (0.39) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL5943202 | 0.87 | SSTR3 (0.45) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL3314831 | 0.85 | TACR1 (0.41) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL8351160 | 0.83 | MMP1 (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL4898719 | 0.80 | TACR1 (0.41) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL3926322 | 0.80 | TACR1 (0.41) | LMNASMN1; SMN2HPGD | |
| SCHEMBL1078320 | 0.78 | TACR1 (0.42) | MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL3513112 | 0.76 | FKBP4 (0.44) | SMN1; SMN2HPGDMAPT | |
| SCHEMBL366333 | 0.76 | TACR1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985361-A | GENETIC ENGINEERING | SANKYO COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |