Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTR1E | P28566 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | MYOC | Q99972 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468592 | 0.94 | MEN1 (0.43) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL9839725 | 0.92 | MEN1 (0.44) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL5943202 | 0.82 | SSTR3 (0.45) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3926322 | 0.80 | TACR1 (0.41) | LMNASMN1; SMN2HPGDMMP9 | |
| SCHEMBL3314831 | 0.79 | TACR1 (0.41) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL8351160 | 0.78 | MMP1 (0.45) | MEN1KMT2AMAPT | |
| SCHEMBL1088019 | 0.78 | MMP9 (0.41) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL644954 | 0.76 | OPRD1 (0.39) | SMN1; SMN2HPGD | |
| SCHEMBL1451494 | 0.75 | MEN1 (0.40) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL1033030 | 0.75 | MMP9 (0.42) | MEN1KMT2ALMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972683-A | THE SUBTILISIN YAB MUTANTS CAN BE USED IN VARIOUS ASPECTS SUCH AS THE QUALITY IMPROVEMENT OF MEAT AND THE PROTEIN PROCESSING FOR FOODSTUFF AND FEEDSTUFF. | NATIONAL SCIENCE COUNCIL (TW) | 1999-10-26 | — | — | US | disclosed |