Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid Diethyl Ester SCHEMBL9840328 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ERAB9AMAPK1 | |
| SCHEMBL9839509 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ERAB9AMAPK1 | |
| SCHEMBL357704 | 0.77 | LMNA (0.68) | ALDH1A1MAPTKDM4ERAB9AMCL1 | |
| SCHEMBL9840309 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ERAB9AMCL1 | |
| SCHEMBL4897408 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ERAB9AMAPK1 | |
| SCHEMBL9750091 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ERAB9AMAPK1 | |
| SCHEMBL12018342 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ERAB9AMCL1 | |
| SCHEMBL9750077 | 0.73 | MAPT (0.53) | ALDH1A1MAPTKDM4ERAB9ASMN1; SMN2 | |
| Padimate A SCHEMBL15372 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAPTKDM4ERAB9AMCL1 | |
| SCHEMBL7536250 | 0.72 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4ERAB9AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057154-A | Colorfastness, stability | RICOH COMPANY, LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |