SCHEMBL9840107

SCHEMBL9840107

O=C(O)CCCCCCCCCCCNc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.61
GLA P06280 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
HPGD P15428 3/20 0.58
ALOX12 P18054 1/20 0.58
MAPT P10636 11/20 0.57
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
TDP1 Q9NUW8 1/20 0.52
HSP90AA1 P07900 1/20 0.51
GAA P10253 4/20 0.49
HDAC3 O15379 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
HDAC4 P56524 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4829828 1.00 ALDH1A1 (0.61) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL9509667 0.94 ALDH1A1 (0.64) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL6259751 0.87 ALDH1A1 (0.59) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL14117517 0.87 ALDH1A1 (0.66) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL18549022 0.87 ALDH1A1 (0.66) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL25210427 0.85 ALDH1A1 (0.69) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL25240545 0.85 ALDH1A1 (0.69) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL4953010 0.83 ALDH1A1 (0.61) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL6673456 0.83 ALDH1A1 (0.61) ALDH1A1GLASMN1; SMN2HPGDALOX12
SCHEMBL15480467 0.82 MEN1 (0.78) ALDH1A1SMN1; SMN2HPGDMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047535-A N-heterocyclic amphiphilic amides YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1991-09-10 US disclosed
EP-0255718-A2 Use of amphiphilic amide compounds in Z-type Langmuir-Blodgett films YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1988-02-10 EP disclosed