Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197916 | 0.70 | ATM (0.58) | MAPTTHRBATMNPC1RAB9A | |
| SCHEMBL10568997 | 0.66 | CASP3 (0.63) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL10569250 | 0.66 | CALM1 (0.62) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL581719 | 0.66 | CASP3 (0.63) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL30928708 | 0.65 | NPC1 (0.35) | HRH3NPC1RAB9ASIGMAR1LMNA | |
| SCHEMBL10533113 | 0.65 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL10571533 | 0.65 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL4055705 | 0.65 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL3220040 | 0.65 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL3220290 | 0.65 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002941-A | Antiarthritic agents, arachidonic acid metabolism | SMITHKLINE BEECHAM CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |