Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073645 | 0.81 | IDH1 (0.35) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL9505759 | 0.68 | LMNA (0.35) | — | |
| SCHEMBL6073371 | 0.61 | POLB (0.37) | MTNR1AMTNR1B | |
| SCHEMBL31180209 | 0.60 | POLB (0.34) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL16799478 | 0.59 | DRD2 (0.36) | HTR2CMTNR1AMTNR1B | |
| SCHEMBL31180129 | 0.59 | POLB (0.33) | — | |
| SCHEMBL5751466 | 0.58 | HRH4 (0.51) | — | |
| SCHEMBL8564261 | 0.58 | KDM4E (0.34) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL31180259 | 0.58 | DRD2 (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL22337647 | 0.57 | MTNR1A (0.50) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986934-A | SPIROBENZOXAZINE PYRROLOPYRIDINE COMPOUNDS, EYEGLASSES | PPG INDUSTRIES, INC. (US) | 1991-01-22 | — | — | US | disclosed |