Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272903 | 0.86 | LTA4H (0.41) | TSHRALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL7540188 | 0.86 | ALOX15 (0.48) | ALDH1A1KDM4EALOX15L3MBTL1MAPK1 | |
| SCHEMBL9271566 | 0.79 | NDUFS8 (0.35) | TSHRNPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3476978 | 0.79 | NPC1 (0.42) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9274162 | 0.77 | NDUFS8 (0.36) | NPC1ALDH1A1RAB9AKDM4ELMNA | |
| SCHEMBL29232611 | 0.76 | NPC1 (0.40) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL11209912 | 0.76 | NPC1 (0.40) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL938005 | 0.75 | NPC1 (0.42) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL3260151 | 0.75 | CHRNB2 (0.44) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL31124123 | 0.75 | NPC1 (0.42) | TSHRNPC1ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077046-A | Plant extracts; mannaliam dolichols intermediates | KURARAY CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-5012018-A | Extending polyisoprene chain using copper catalyst | KURARAY CO., LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4886904-A | CONTAINING CIS AND TRANS ISOPRENE UNITS | KURARAY CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0054753-B1 | POLYPRENYL COMPOSITION OR COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | KURARAY CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0054753-A1 | Polyprenyl composition or compounds and process for the production thereof | KURARAY CO., LTD. (JP) | 1982-06-30 | — | — | EP | disclosed |