Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841866 | 0.83 | CA2 (0.43) | ALDH1A1MAPTGAATDP1HDAC6 | |
| SCHEMBL9841782 | 0.81 | KDR (0.48) | ALDH1A1MAPTGAATDP1HDAC6 | |
| SCHEMBL9841770 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTGAATDP1HDAC6 | |
| SCHEMBL9842198 | 0.76 | PTGS1 (0.44) | ALDH1A1MAPTGAATDP1HDAC6 | |
| SCHEMBL9842148 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTGAATDP1HDAC6 | |
| SCHEMBL9841838 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTGAATDP1CA2 | |
| SCHEMBL18459329 | 0.74 | CA2 (0.61) | ALDH1A1MAPTGAATDP1CA2 | |
| SCHEMBL10577907 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTGAATDP1CA2 | |
| SCHEMBL9841894 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTGAATDP1CA2 | |
| SCHEMBL10870243 | 0.70 | NFKB1 (0.45) | ALDH1A1MAPTGAATDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | claimed |
| US-5059598-A | Antiinflammatory agents; lipoxygenase inhibitors; arthritis; asthma | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-4868183-A | ANTIINFLAMMATORY, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | disclosed |