Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214380 | 0.69 | ALDH1A1 (0.49) | ALDH1A1PRMT5WDR77HTTMAPT | |
| SCHEMBL9216185 | 0.69 | ALDH1A1 (0.49) | ALDH1A1PRMT5WDR77HTTMAPT | |
| SCHEMBL9215446 | 0.69 | ALDH1A1 (0.49) | ALDH1A1PRMT5WDR77HTTMAPT | |
| SCHEMBL2967442 | 0.67 | PRMT5 (0.72) | ALDH1A1PRMT5WDR77PKMGAA | |
| SCHEMBL1164097 | 0.67 | PRMT5 (0.72) | ALDH1A1PRMT5WDR77PKMGAA | |
| SCHEMBL9645456 | 0.67 | PRMT5 (0.72) | ALDH1A1PRMT5WDR77PKMGAA | |
| SCHEMBL11756385 | 0.66 | PRMT5 (0.48) | ALDH1A1PRMT5WDR77HTTKCNJ1 | |
| SCHEMBL11756369 | 0.66 | PRMT5 (0.48) | ALDH1A1PRMT5WDR77HTTKCNJ1 | |
| SCHEMBL394196 | 0.65 | ALDH1A1 (0.49) | ALDH1A1PRMT5WDR77MAPTMEN1 | |
| SCHEMBL31715477 | 0.65 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |