Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842160 | 1.00 | GLO1 (0.46) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL9475845 | 0.85 | PDCD1 (0.51) | GLO1HTTAKR1C3KDM4EPDCD1 | |
| SCHEMBL9475839 | 0.85 | PDCD1 (0.51) | GLO1HTTAKR1C3KDM4EPDCD1 | |
| SCHEMBL30938425 | 0.78 | KDM4E (0.55) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL9476015 | 0.78 | GLO1 (0.50) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL9476020 | 0.78 | GLO1 (0.50) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL31634782 | 0.78 | KDM4E (0.55) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL7551989 | 0.78 | KDM4E (0.55) | GLO1HTTTDP1ALDH1A1GLA | |
| SCHEMBL9476279 | 0.76 | AKR1C3 (0.51) | GLO1HTTTDP1ALDH1A1GLA | |
| Balazipone SCHEMBL636109 | 0.76 | PDCD1 (0.55) | GLO1TDP1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |