Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | IL2 | P60568 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842940 | 0.80 | CNR1 (0.53) | CNR1IL2 | |
| SCHEMBL9842883 | 0.79 | CNR1 (0.52) | CNR1IL2 | |
| SCHEMBL9842945 | 0.79 | HSD17B2 (0.38) | CNR1NPC1RAB9ATP53MAPT | |
| SCHEMBL9842919 | 0.75 | CYP1A2 (0.42) | CNR1NPC1RAB9ATP53MAPT | |
| SCHEMBL9842957 | 0.74 | CNR1 (0.45) | CNR1NPC1RAB9ATP53MAPT | |
| SCHEMBL9842925 | 0.74 | CNR1 (0.39) | CNR1NPC1RAB9ATP53MAPT | |
| SCHEMBL9842822 | 0.72 | NPC1 (0.43) | NPC1RAB9ATP53MAPTNFKB1 | |
| SCHEMBL9842938 | 0.72 | IL2 (0.39) | CNR1NPC1RAB9ATP53MAPT | |
| SCHEMBL9843027 | 0.71 | CNR1 (0.52) | CNR1RORCNPC1RAB9ATP53 | |
| SCHEMBL9842892 | 0.70 | HDAC6 (0.44) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |