Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842993 | 0.88 | IL2 (0.48) | NPC1RAB9ACYP1A2MAPK1APOBEC3A | |
| SCHEMBL9842919 | 0.87 | CYP1A2 (0.42) | NPC1RAB9AALDH1A1RXFP1HPGD | |
| SCHEMBL9842940 | 0.84 | CNR1 (0.53) | CYP1A2MAPK1APOBEC3AAPOBEC3GIL2 | |
| SCHEMBL9843028 | 0.84 | CNR1 (0.51) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL9843027 | 0.83 | CNR1 (0.52) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9842938 | 0.81 | IL2 (0.39) | NPC1RAB9AKDRCYP1A2MAPK1 | |
| SCHEMBL9842925 | 0.81 | CNR1 (0.39) | NPC1RAB9ACYP1A2MAPK1APOBEC3A | |
| SCHEMBL9842892 | 0.81 | HDAC6 (0.44) | IL2 | |
| SCHEMBL9842991 | 0.80 | CNR1 (0.54) | NPC1RAB9AALDH1A1CYP1A2MAPK1 | |
| SCHEMBL9842960 | 0.79 | KDR (0.42) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |