Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 4/20 | 0.35 |
| ▸ | SELP | P16109 | 4/20 | 0.35 |
| ▸ | SELE | P16581 | 2/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
| ▸ | IL2 | P60568 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842919 | 0.77 | CYP1A2 (0.42) | HSD17B2HSD17B1NPC1TP53MAPT | |
| SCHEMBL9842940 | 0.77 | CNR1 (0.53) | CNR1CYP1A2MAPK1APOBEC3AAPOBEC3G | |
| SCHEMBL9842925 | 0.76 | CNR1 (0.39) | NPC1TP53MAPTNFKB1RAB9A | |
| SCHEMBL9843027 | 0.75 | CNR1 (0.52) | HSD17B2HSD17B1NPC1TP53MAPT | |
| SCHEMBL9842959 | 0.74 | NPC1 (0.54) | NPC1TP53RAB9AMEN1KMT2A | |
| SCHEMBL9842993 | 0.74 | IL2 (0.48) | NPC1RAB9ACYP1A2MAPK1APOBEC3A | |
| SCHEMBL9843028 | 0.74 | CNR1 (0.51) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9842938 | 0.74 | IL2 (0.39) | NPC1TP53MAPTNFKB1RAB9A | |
| SCHEMBL9842991 | 0.73 | CNR1 (0.54) | HSD17B2HSD17B1NPC1TP53MAPT | |
| SCHEMBL9842957 | 0.71 | CNR1 (0.45) | NPC1TP53MAPTNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |