Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909551 | 0.87 | POLB (0.62) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL9428604 | 0.83 | POLB (0.57) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL20679552 | 0.81 | RNF4 (0.59) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL8277402 | 0.80 | L3MBTL1 (0.77) | TP53MAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL24323392 | 0.79 | L3MBTL1 (0.52) | MAPTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL9842935 | 0.79 | TP53 (0.66) | TP53MAPTALDH1A1KMT2AMTNR1B | |
| SCHEMBL9842944 | 0.79 | POLB (0.77) | TP53POLBMAPTALDH1A1KMT2A | |
| SCHEMBL5952262 | 0.78 | MEN1 (0.61) | TP53POLBMAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL19464660 | 0.78 | KMT2A (0.56) | TP53POLBMAPTAPOBEC3AAPOBEC3G | |
| SCHEMBL9842921 | 0.78 | EPHX2 (0.63) | TP53ALDH1A1KMT2AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |