Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413287 | 0.92 | PTGS1 (0.40) | PTGS1PTGS2MGLLALDH1A1HPGD | |
| SCHEMBL325404 | 0.90 | PTGS1 (0.48) | PTGS1PTGS2MGLLALDH1A1HPGD | |
| SCHEMBL977159 | 0.82 | MAP3K14 (0.38) | LMNAMAPTPKMSMN1; SMN2 | |
| SCHEMBL30402863 | 0.78 | — | — | |
| SCHEMBL20589363 | 0.77 | PRKCA (0.38) | LMNAMAPTPKM | |
| SCHEMBL723395 | 0.76 | — | — | |
| SCHEMBL6551912 | 0.76 | HSD17B10 (0.39) | ALDH1A1 | |
| SCHEMBL8505753 | 0.75 | NPC1 (0.38) | ALDH1A1LMNAMAPTPKMRECQL | |
| SCHEMBL13386960 | 0.75 | MAP3K14 (0.32) | — | |
| SCHEMBL29412565 | 0.74 | MGLL (0.43) | PTGS1PTGS2MGLLALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521303-B | Nanometer vesicle loaded with PD-L1 antibody and STING agonist together and preparation method and application thereof | 中山大学附属第一医院 | 2024-01-02 | — | — | CN | claimed |
| CN-114848844-B | Nano-engineering stem cell anti-tumor targeted drug delivery system and preparation method and application thereof | 中国药科大学 | 2023-06-20 | — | — | CN | claimed |
| CN-115947775-B | Method for preparing compound (I), compound (I) and application thereof | 北京先通国际医药科技股份有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-115947775-A | Method for preparing compound (I), compound (I) and application thereof | 北京先通国际医药科技股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-113318242-B | Tumor-targeted multifunctional non-viral gene vector and preparation method and application thereof | 四川大学华西医院 | 2023-03-10 | — | — | CN | claimed |
| CN-114854045-A | Polyamino acid hydrogel and preparation method and application thereof | 北京大学 | 2022-08-05 | — | — | CN | claimed |
| CN-114306586-A | Tumor vaccine based on TF antigen and chitosan oligosaccharide endogenous adjuvant, method and application | 天津科技大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113769169-A | Anticoagulation cell adhesion-promoting biological valve material and preparation method thereof | 四川大学华西医院 | 2021-12-10 | — | — | CN | claimed |
| CN-113521303-A | Nano vesicle jointly loaded with PD-L1 antibody and STING agonist, and preparation method and application thereof | 中山大学附属第一医院 | 2021-10-22 | — | — | CN | claimed |
| CN-113318242-A | Tumor-targeted multifunctional non-viral gene vector and preparation method and application thereof | 四川大学华西医院 | 2021-08-31 | — | — | CN | claimed |
| CN-106755027-B | Non-viral gene vector for gene delivery and preparation method and application thereof | 四川大学华西医院 | 2021-01-15 | — | — | CN | claimed |
| CN-106729777-B | Nano chitosan ultrasonic microbubble targeting prostate cancer cells and preparation and application thereof | 华南理工大学 | 2020-01-14 | — | — | CN | claimed |
| CN-117883556-A | Antigen capturing nano-particles and application of preparation method thereof in tumor immunotherapy | 苏州大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-111819184-B | Synthetic oligosaccharide derivatives as vaccine against bordetella pertussis | 芬兰疫苗研究所 | 2024-01-12 | — | — | CN | disclosed |
| CN-113521303-B | Nanometer vesicle loaded with PD-L1 antibody and STING agonist together and preparation method and application thereof | 中山大学附属第一医院 | 2024-01-02 | — | — | CN | disclosed |
| CN-117224695-A | Leptin-polyamino acid conjugate, preparation method and application thereof | 苏州沈美生物医药有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-5274119-A | Vicinal diols | THE DOW CHEMICAL COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0519554-A1 | Conjugates of the class II protein of the outer membrane of neisseria meningitidis and of HIV-1 related peptides | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| EP-0467714-A1 | The class II protein of the outer membrane of neisseria meningitidis | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0467700-A2 | Coconjugate vaccines comprising immunogenic protein, HIV related peptides, and anionic moieties | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |