Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201955 | 0.86 | AKR1B1 (0.42) | — | |
| SCHEMBL28966834 | 0.86 | AKR1B1 (0.42) | — | |
| SCHEMBL19314096 | 0.78 | GABRA1 (0.38) | — | |
| SCHEMBL13213096 | 0.78 | PNMT (0.40) | — | |
| SCHEMBL9822606 | 0.78 | CHRNE (0.33) | — | |
| SCHEMBL30753431 | 0.77 | HSP90AA1 (0.33) | GAANPSR1 | |
| SCHEMBL7650362 | 0.76 | PARP1 (0.44) | GAA | |
| SCHEMBL16774069 | 0.74 | ALDH1A1 (0.34) | GAA | |
| SCHEMBL9822610 | 0.73 | — | — | |
| SCHEMBL28305445 | 0.72 | HTR2B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443312-A2 | 2,4,8-trisubstituted-3H-6H-1,4,5a,8a-tetraazaacenaphthylene-3,5-(4H)-diones | AMERICAN CYANAMID COMPANY (US) | 1991-08-28 | — | — | EP | disclosed |