Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNE | Q04844 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19314096 | 0.81 | GABRA1 (0.38) | — | |
| SCHEMBL13213096 | 0.81 | PNMT (0.40) | — | |
| SCHEMBL9822610 | 0.80 | — | — | |
| SCHEMBL28305445 | 0.79 | HTR2B (0.35) | — | |
| SCHEMBL9843338 | 0.78 | GAA (0.34) | — | |
| SCHEMBL16774069 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL6749423 | 0.75 | BCL2L1 (0.41) | — | |
| SCHEMBL9822478 | 0.71 | ADRA2A (0.36) | — | |
| SCHEMBL19692682 | 0.71 | PARP1 (0.34) | — | |
| SCHEMBL31170847 | 0.71 | PARP10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570414-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | Bristol-Myers Squibb Company (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011025070-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | WO | disclosed |
| EP-0230967-B1 | BENZAZECINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-23 | — | — | EP | disclosed |
| EP-0230967-A2 | Benzazecine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-08-05 | — | — | EP | disclosed |