Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19008259 | 0.92 | POLB (0.45) | POLBNPSR1MAPTALDH1A1NR1I2 | |
| SCHEMBL1305579 | 0.81 | POLB (0.59) | POLBNPSR1MAPTALDH1A1NR1I2 | |
| SCHEMBL7738531 | 0.77 | TSHR (0.44) | POLBNPSR1MAPTALDH1A1NR1I2 | |
| SCHEMBL7738533 | 0.75 | NR1I2 (0.53) | POLBNPSR1MAPTALDH1A1NR1I2 | |
| SCHEMBL735674 | 0.75 | TSHR (0.52) | POLBNPSR1MAPTNR1I2MAPK1 | |
| SCHEMBL514913 | 0.74 | NFE2L2 (0.43) | POLBNPSR1MAPTNR1I2MAPK1 | |
| SCHEMBL2902839 | 0.74 | NR1I2 (0.42) | POLBNPSR1MAPTNR1I2MAPK1 | |
| SCHEMBL514914 | 0.74 | NFE2L2 (0.43) | POLBNPSR1MAPTNR1I2MAPK1 | |
| SCHEMBL2902845 | 0.74 | NR1I2 (0.42) | POLBNPSR1MAPTNR1I2MAPK1 | |
| SCHEMBL9714149 | 0.74 | POLB (0.45) | POLBNPSR1MAPTALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | claimed |
| EP-0333758-B1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS | COMMW SCIENT IND RES ORG (AU) | 1995-11-02 | — | — | EP | claimed |
| US-10982071-B2 | Sulfonic acid esters as regulators in radical polymerization reactions | IVOCLAR VIVADENT AG (LI) | 2021-04-20 | — | — | US | disclosed |
| US-10736820-B2 | Materials which can be cured by chain transfer polymerization | IVOCLAR VIVADENT AG (LI) | 2020-08-11 | — | — | US | disclosed |
| US-10342744-B2 | Compositions with controlled network structure | IVOCLAR VIVADENT AG (LI) | 2019-07-09 | — | — | US | disclosed |
| EP-3292157-B1 | SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2019-04-24 | — | — | EP | disclosed |
| EP-3090722-B1 | DENTAL MATERIALS WHICH CAN BE HARDENED BY CHAIN-TRANSFER POLYMERIZATION | IVOCLAR VIVADENT AG (LI) | 2019-01-09 | — | — | EP | disclosed |
| US-20180142082-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2018-05-24 | — | — | US | disclosed |
| US-20180142082-A1 | SULFONIC ACID ESTERS AS REGULATORS IN RADICAL POLYMERIZATION REACTIONS | IVOCLAR VIVADENT AG (LI) | 2018-05-24 | — | — | US | disclosed |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-08 | — | — | US | disclosed |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-08 | — | — | US | disclosed |
| EP-2965740-A1 | Dental materials with debonding on demand properties | Ivoclar Vivadent AG (LI) | 2016-01-13 | — | — | EP | disclosed |
| US-6197905-B1 | VINYL ETHER CHAIN TRANSFER AGENT TERMINATES THE GROWTH OF THE POLYMER CHAIN BY ADDITION TO THE PROPAGATING POLYMER RADICAL FOLLOWED BY EXPULSION OF A RADICAL WHICH THEN INITIATES ANOTHER POLYMER CHAIN | COMMONWEALTH SCIENTIFIC & INDUSTRIAL RESARCH ORGANIZATION (AU) | 2001-03-06 | — | — | US | disclosed |
| US-5932675-A | Free-radical chain transfer polymerization process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-08-03 | — | — | US | disclosed |
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0333758-B1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS | COMMW SCIENT IND RES ORG (AU) | 1995-11-02 | — | — | EP | disclosed |
| US-5385996-A | Control of molecular weight and end-group functionality of polymers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-01-31 | — | — | US | disclosed |
| EP-0333758-A4 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. | COMMW SCIENT IND RES ORG (AU) | 1990-05-14 | — | — | EP | disclosed |
| EP-0333758-A1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. | COMMW SCIENT IND RES ORG (AU) | 1989-09-27 | — | — | EP | disclosed |
| WO-1988004304-A1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 1988-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342744-B2 | Compositions with controlled network structure | NCLN, RAD51, SMCHD1 | POLB 429/4885NPSR1 4579/4885MAPT 894/4885 |
| US-10736820-B2 | Materials which can be cured by chain transfer polymerization | H1-10, CNOT1, C1S | POLB 857/4885NPSR1 1425/4885MAPT 2240/4885 |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | DCLRE1A, RAD51, TERB1 | POLB 407/4885NPSR1 3402/4885MAPT 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.