Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843340 | 0.73 | MAOA (0.38) | TSHRMAOAMAOBCYP2C9CYP1A2 | |
| SCHEMBL8722927 | 0.70 | ALDH1A1 (0.39) | MAOAMAOBCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL3752087 | 0.68 | MAOA (0.50) | MAOAMAOBCYP3A4ALOX15ALDH1A1 | |
| SCHEMBL9330920 | 0.67 | MAOA (0.48) | TSHRMAOAMAOBCYP3A4ALOX15 | |
| SCHEMBL17044686 | 0.66 | MAOA (0.44) | MAOAMAOBLMNAMEN1KMT2A | |
| SCHEMBL58239 | 0.65 | MAOA (0.47) | TSHRMAOAMAOBALDH1A1CYP2C19 | |
| SCHEMBL18546613 | 0.65 | MAOA (0.47) | TSHRMAOAMAOBCYP3A4ALOX15 | |
| SCHEMBL5143592 | 0.65 | TDP1 (0.57) | TSHRCYP2C9CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9647298 | 0.65 | MAOA (0.42) | TSHRMAOAMAOBCYP3A4ALOX15 | |
| SCHEMBL17594174 | 0.65 | THRB (0.51) | TSHRMAOAMAOBCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |