Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927038 | 0.94 | ALDH1A1 (0.31) | POLBCA12CA1CA2CA7 | |
| SCHEMBL3059991 | 0.81 | POLB (0.34) | POLBCA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL28079593 | 0.79 | POLB (0.33) | POLBCA12CA1CA2CA7 | |
| SCHEMBL1927671 | 0.76 | CA2 (0.41) | POLBCA12CA1CA2CA7 | |
| SCHEMBL8229612 | 0.73 | CA1 (0.45) | POLBCA12CA1CA2CA7 | |
| SCHEMBL1927669 | 0.72 | POLB (0.31) | POLBCA12CA1CA2CA7 | |
| SCHEMBL9843392 | 0.72 | POLB (0.34) | POLBCA12CA1CA2CA7 | |
| SCHEMBL1926045 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL5559189 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL23569219 | 0.69 | CA2 (0.35) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819125-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031492-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-10-10 | — | — | WO | disclosed |