Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843680 | 0.78 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8515583 | 0.77 | — | — | |
| SCHEMBL9843662 | 0.75 | MAPT (0.37) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9843881 | 0.75 | MAPT (0.37) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL16460603 | 0.74 | — | — | |
| SCHEMBL2229077 | 0.70 | LMNA (0.45) | HPGDHTTMAPT | |
| SCHEMBL28619888 | 0.68 | POLB (0.45) | HPGDHTTNPSR1 | |
| SCHEMBL28868241 | 0.68 | LMNA (0.42) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5587629 | 0.67 | FFAR1 (0.46) | GCGRFFAR1NPC1HPGDMAPK1 | |
| SCHEMBL12251371 | 0.67 | CASP1 (0.41) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |