Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843943 | 0.79 | KMT2A (0.46) | KMT2ALMNAMEN1 | |
| SCHEMBL9843883 | 0.76 | KMT2A (0.50) | KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL9843892 | 0.75 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL2147650 | 0.70 | KMT2A (0.65) | KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL11580793 | 0.69 | NPC1 (0.63) | LPAR1KMT2ASMN1; SMN2LMNAANPEP | |
| SCHEMBL9680507 | 0.69 | SOAT2 (0.55) | KMT2ASMN1; SMN2LMNAMEN1 | |
| Benzene SCHEMBL11580795 | 0.68 | ANPEP (0.64) | LPAR1KMT2ASMN1; SMN2LMNAANPEP | |
| SCHEMBL9680252 | 0.68 | LPAR1 (0.58) | LPAR1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL9844183 | 0.67 | KMT2A (0.50) | KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL19449467 | 0.67 | ANPEP (0.66) | LPAR1KMT2ASMN1; SMN2ANPEPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |