Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843943 | 0.77 | KMT2A (0.46) | LMNAMEN1KMT2ANPC1 | |
| SCHEMBL9843835 | 0.75 | LPAR1 (0.59) | MAPTLMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL9843883 | 0.75 | KMT2A (0.50) | LMNASMN1; SMN2MEN1KMT2ASOAT2 | |
| SCHEMBL9678916 | 0.74 | MEN1 (0.47) | ALDH1A1MAPTNPSR1LMNAGAA | |
| SCHEMBL9843942 | 0.72 | MEN1 (0.49) | LMNASMN1; SMN2MEN1KMT2ASOAT2 | |
| SCHEMBL2147650 | 0.69 | KMT2A (0.65) | LMNASMN1; SMN2MEN1KMT2ASOAT2 | |
| SCHEMBL855984 | 0.69 | SOAT2 (0.47) | LMNAKMT2ASOAT2ACAT1SOAT1 | |
| SCHEMBL9680035 | 0.69 | KMT2A (0.43) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL9680507 | 0.68 | SOAT2 (0.55) | LMNASMN1; SMN2MEN1KMT2ASOAT2 | |
| SCHEMBL9851017 | 0.67 | KMT2A (0.46) | ALDH1A1MAPTLMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |