Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2147650 | 0.79 | KMT2A (0.65) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL9680507 | 0.78 | SOAT2 (0.55) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL9843943 | 0.77 | KMT2A (0.46) | KMT2AMEN1LMNA | |
| SCHEMBL9844183 | 0.76 | KMT2A (0.50) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL9681123 | 0.76 | SOAT2 (0.61) | KMT2ASOAT2SOAT1LMNASMN1; SMN2 | |
| SCHEMBL9843835 | 0.76 | LPAR1 (0.59) | KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9843892 | 0.75 | ALDH1A1 (0.43) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL8962491 | 0.75 | KMT2A (0.58) | KMT2AMEN1SOAT2SOAT1LMNA | |
| SCHEMBL11143056 | 0.74 | ALDH1A1 (0.58) | KMT2ASOAT2SOAT1LMNAUBE2M | |
| SCHEMBL9679656 | 0.72 | SOAT2 (0.60) | KMT2AMEN1SOAT2SOAT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |