Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597828 | 0.91 | NPSR1 (0.48) | NPSR1IDO1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL3583043 | 0.89 | NPSR1 (0.47) | NPSR1IDO1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL16726994 | 0.86 | NPSR1 (0.41) | NPSR1IDO1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL10623268 | 0.84 | CA1 (0.53) | NPSR1IDO1ALOX5ALDH1A1KDM4E | |
| SCHEMBL26181059 | 0.84 | CA1 (0.48) | NPSR1IDO1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL4679010 | 0.83 | IDO1 (0.56) | NPSR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1960375 | 0.82 | KDM4E (0.46) | NPSR1ALDH1A1KDM4ECYP3A4CYP2D6 | |
| SCHEMBL26181057 | 0.81 | ALDH1A1 (0.49) | NPSR1IDO1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL20241572 | 0.80 | CYP26A1 (0.40) | NPSR1IDO1KDM4EDAOCYP3A4 | |
| SCHEMBL7724329 | 0.80 | ALDH1A1 (0.53) | NPSR1IDO1ALOX5SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051915-A1 | METHOD FOR PREPARING 2-HYDROXY-5-[2-(4-(TRIFLUOROMETHYLPHENYL)ETHYLAMINO)]BENZOIC ACID | GNT PHARMA CO., LTD. (KR) | 2024-02-15 | — | — | US | disclosed |
| EP-4261201-A1 | METHOD FOR PREPARING 2-HYDROXY-5-[2-(4-(TRIFLUOROMETHYLPHENYL)ETHYLAMINO)]BENZOIC ACID | GNT Pharma Co., Ltd (KR) | 2023-10-18 | — | — | EP | disclosed |
| CN-112409201-B | Preparation method of 2-hydroxy-5- [2- (4- (trifluoromethylphenyl) ethylamino) ] benzoic acid | 浙江普洛家园药业有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112409201-A | Preparation method of 2-hydroxy-5- [2- (4- (trifluoromethylphenyl) ethylamino) ] benzoic acid | 浙江普洛家园药业有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-20150126516-A1 | PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126516-A1 | PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126516-A1 | PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2845851-A1 | PIPERIDINE COMPOUND AND PEST-CONTROL USE THEREFORE | Sumitomo Chemical Company Limited (JP) | 2015-03-11 | — | — | EP | disclosed |
| CN-104302623-A | Piperidine compound and pest-control use therefore | SUMITOMO CHEMICAL CO | 2015-01-21 | — | — | CN | disclosed |
| US-20100004459-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-0714894-A1 | 3-(1,2,3,6-tetrahydro-(1-alkylenearyl)-4-pyridinyl)- and 3-(1-alkylenearyl)-4-piperidinyl-1h-indoles: new 5-HT1f agonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5521197-A | ANALGESICS USING SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0144729-B1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4681879-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4608374-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004459-A1 | 2-PHENYLNICOTINIC ACID DERIVATIVE | XDH, NUDT1, PNPO | NPSR1 2928/4885IDO1 1760/4885ALOX5 193/4885 |
| US-20240051915-A1 | METHOD FOR PREPARING 2-HYDROXY-5-[2-(4-(TRIFLUOROMETHYLPHENYL)ETHYLAMINO)]BENZOIC ACID | HPD, HAAO, HAO2 | NPSR1 4384/4885IDO1 3473/4885ALOX5 550/4885 |
| US-20150126516-A1 | PIPERIDINE COMPOUND AND ITS USE IN PEST CONTROL | ZYX, CXXC5, CNBP | NPSR1 346/4885IDO1 1232/4885ALOX5 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.