Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156285 | 1.00 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL9157298 | 1.00 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL22512589 | 0.91 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL19983719 | 0.90 | ABCG2 (0.64) | TK1ABCG2ABCB1 | |
| SCHEMBL9083351 | 0.89 | TK1 (0.52) | TK1ABCG2ABCB1 | |
| SCHEMBL12865101 | 0.89 | ABCG2 (0.58) | TK1ABCG2ABCB1 | |
| SCHEMBL17635438 | 0.89 | ABCG2 (0.58) | TK1ABCG2ABCB1 | |
| SCHEMBL9081764 | 0.89 | TK1 (0.46) | TK1ABCG2ABCB1 | |
| SCHEMBL9856524 | 0.89 | LMNA (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL9843870 | 0.89 | TK1 (0.54) | TK1ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472019-B1 | Process for producing 3'-deoxy-3'-fluorothymidine | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 1996-11-20 | — | — | EP | claimed |
| US-5166327-A | PROCESS FOR PRODUCING 3'-DEOXY-3-'-FLUOROTHYMIDINE | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| EP-0472019-A1 | Process for producing 3'-deoxy-3'-fluorothymidine | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-02-26 | — | — | EP | claimed |
| US-20110039798-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2011-02-17 | — | — | US | disclosed |
| EP-0472019-B1 | Process for producing 3'-deoxy-3'-fluorothymidine | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | disclosed |
| US-5166327-A | PROCESS FOR PRODUCING 3'-DEOXY-3-'-FLUOROTHYMIDINE | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5153180-A | Used for treating aids | BURROUGHS WELLCOME CO. | 1992-10-06 | — | — | US | disclosed |
| EP-0472019-A1 | Process for producing 3'-deoxy-3'-fluorothymidine | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039798-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | SAMHD1, TLR3, MAVS | TK1 156/4885ABCG2 325/4885ABCB1 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.