Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4542716 | 0.97 | SMN1; SMN2 (0.40) | SMN1; SMN2GABRA1GABRG2GABRB3NLRP3 | |
| SCHEMBL28944746 | 0.80 | GABRA1 (0.34) | SMN1; SMN2GABRA1GABRG2GABRB3NLRP3 | |
| SCHEMBL7909023 | 0.79 | GABRA1 (0.43) | SMN1; SMN2GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL9844148 | 0.78 | KMT2A (0.41) | LMNAKMT2AMEN1 | |
| SCHEMBL9844435 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL4533374 | 0.75 | ALDH1A1 (0.38) | NLRP3LMNACYP1A2CYP3A4HPGD | |
| SCHEMBL9177867 | 0.74 | GABRA1 (0.46) | SMN1; SMN2GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL7937857 | 0.73 | GABRA1 (0.45) | SMN1; SMN2GABRA1GABRG2GABRB3LMNA | |
| Hydrochloric Acid SCHEMBL4534476 | 0.71 | CA2 (0.36) | GABRA1NLRP3CA2TSHRGABRB2 | |
| SCHEMBL9082255 | 0.70 | SCN5A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |