Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844362 | 0.80 | — | — | |
| SCHEMBL9843890 | 0.78 | SMN1; SMN2 (0.41) | KMT2ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL4542716 | 0.76 | SMN1; SMN2 (0.40) | KMT2ALMNAMEN1 | |
| SCHEMBL9844435 | 0.74 | — | — | |
| SCHEMBL9844387 | 0.74 | ALOX5 (0.44) | KMT2ALMNAALOX5MEN1GAA | |
| SCHEMBL17993540 | 0.70 | ALDH1A1 (0.65) | KMT2ALMNAMEN1 | |
| SCHEMBL5502714 | 0.69 | ALDH1A1 (0.50) | KMT2AMEN1GAA | |
| SCHEMBL9723407 | 0.69 | KMT2A (0.39) | KMT2ALMNAMEN1 | |
| SCHEMBL17962437 | 0.67 | KMT2A (0.40) | KMT2ALMNAALOX5MEN1 | |
| SCHEMBL9843880 | 0.66 | SOAT1 (0.53) | KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |