Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115137 | 0.90 | MITF (0.57) | MITFCA1CA2CA4CA9 | |
| SCHEMBL16908331 | 0.87 | CA1 (0.55) | MITFCA1CA2CA4CA9 | |
| SCHEMBL27629296 | 0.82 | TDP1 (0.51) | MITFCA1CA2CA4CA9 | |
| SCHEMBL5160892 | 0.81 | SLC6A4 (0.57) | MITFCA1CA2CA4CA9 | |
| SCHEMBL27784843 | 0.79 | SLC6A2 (0.61) | MITFCA1CA2CA4CA9 | |
| SCHEMBL4584365 | 0.79 | CA1 (0.63) | MITFCA1CA2CA4CA9 | |
| SCHEMBL1415727 | 0.78 | SLC6A2 (0.63) | MITFCA1CA2CA4CA9 | |
| SCHEMBL6936570 | 0.78 | SLC6A2 (0.63) | MITFCA1CA2CA4CA9 | |
| SCHEMBL30499280 | 0.78 | L3MBTL1 (0.37) | CA1CA2CA4CA9TDP1 | |
| SCHEMBL27505917 | 0.78 | SLC6A2 (0.63) | MITFCA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |