Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.68 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844070 | 0.94 | SIGMAR1 (0.68) | SIGMAR1GRM2HTR7 | |
| SCHEMBL9844117 | 0.92 | SIGMAR1 (0.68) | SIGMAR1GRM2 | |
| SCHEMBL9844036 | 0.92 | SIGMAR1 (0.68) | SIGMAR1GRM2 | |
| SCHEMBL9502924 | 0.91 | SIGMAR1 (0.82) | SIGMAR1GRM2 | |
| SCHEMBL9679057 | 0.91 | SIGMAR1 (0.82) | SIGMAR1GRM2 | |
| SCHEMBL9844324 | 0.91 | SIGMAR1 (0.76) | SIGMAR1GRM2 | |
| SCHEMBL9844284 | 0.89 | SIGMAR1 (0.54) | SIGMAR1GRM2 | |
| SCHEMBL9844046 | 0.89 | MAOA (0.57) | SIGMAR1GRM2 | |
| SCHEMBL9844250 | 0.88 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL9844032 | 0.88 | SIGMAR1 (0.65) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |