Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986668 | 0.95 | TDP1 (0.73) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11354710 | 0.94 | TDP1 (0.62) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL31746274 | 0.93 | TDP1 (0.71) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL4806447 | 0.93 | TDP1 (0.71) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6821332 | 0.93 | TDP1 (0.71) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2705499 | 0.91 | ALDH1A1 (0.57) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL10962809 | 0.91 | TDP1 (0.67) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL529612 | 0.89 | TDP1 (0.63) | TDP1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2705485 | 0.88 | TDP1 (0.53) | TDP1LMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10655768 | 0.86 | TDP1 (0.70) | TDP1LMNAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-08-05 | — | — | US | disclosed |
| CN-116761635-A | BCL-XL inhibitor antibody drug conjugates and methods of use thereof | 诺华股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-11655360-B2 | Gas-barrier resin composition and use thereof | SHOWA DENKO K.K. (JP) | 2023-05-23 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| CN-110799600-B | Gas barrier resin composition and use thereof | 昭和电工株式会社 | 2022-06-21 | — | — | CN | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3864021-A1 | COMPOSITIONS AND METHODS FOR VISIBLE-LIGHT-CONTROLLED RUTHENIUM-CATALYZED OLEFIN METATHESIS | The Trustees of Columbia University in the City of New York (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20210147669-A1 | GAS-BARRIER RESIN COMPOSITION AND USE THEREOF | SHOWA DENKO K.K. (JP) | 2021-05-20 | — | — | US | disclosed |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2014-08-14 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
| WO-2013045876-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-04-04 | — | — | WO | disclosed |
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | TDP1 2445/4885LMNA 4173/4885ALDH1A1 1395/4885 |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | TDP1 2445/4885LMNA 4173/4885ALDH1A1 1395/4885 |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | TDP1 695/4885LMNA 4427/4885ALDH1A1 4132/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | TDP1 2445/4885LMNA 4173/4885ALDH1A1 1395/4885 |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | OSBP, CYCS, OSBPL3 | TDP1 3602/4885LMNA 4107/4885ALDH1A1 4330/4885 |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | TDP1 695/4885LMNA 4427/4885ALDH1A1 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.