Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568779 | 0.90 | ESR1 (0.48) | TDP1LMNAMAPK1SLC6A2KMT2A | |
| SCHEMBL9844077 | 0.89 | TDP1 (0.70) | TDP1LMNAF2MAPK1HIF1A | |
| SCHEMBL21986668 | 0.88 | TDP1 (0.73) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL9568783 | 0.87 | ALDH1A1 (0.58) | TDP1LMNAMAPK1SLC6A2ALDH1A1 | |
| SCHEMBL6821332 | 0.86 | TDP1 (0.71) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL31746274 | 0.86 | TDP1 (0.71) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL4806447 | 0.86 | TDP1 (0.71) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL24370565 | 0.84 | CYP3A4 (0.54) | TDP1LMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL11354710 | 0.84 | TDP1 (0.62) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10962809 | 0.84 | TDP1 (0.67) | TDP1LMNAMAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264011-A | Preparation method of ortho-bis-azide compound | 安徽中医药大学 | 2025-01-07 | — | — | CN | claimed |
| CN-118084725-A | 1-Cyano 2-hydroxy compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | claimed |
| EP-4003988-B1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | SERVIER LAB (FR) | 2026-05-20 | — | — | EP | disclosed |
| EP-4691242-A1 | PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025214612-A1 | PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025201636-A1 | PESTICIDALLY-ACTIVE 2,2-DIHALOCYCLOPROPYL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-02 | — | — | WO | disclosed |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-08-05 | — | — | US | disclosed |
| US-12312377-B2 | Biconjugatable labels and methods of use | Quantum-Si Incorporated (US) | 2025-05-27 | — | — | US | disclosed |
| US-20250059157-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2025-02-20 | — | — | US | disclosed |
| CN-119264011-A | Preparation method of ortho-bis-azide compound | 安徽中医药大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-118084725-A | 1-Cyano 2-hydroxy compound and preparation method thereof | 南京工业大学 | 2024-05-28 | — | — | CN | disclosed |
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-7244721-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244721-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070055448-A1 | Primary rat hepatocyte toxicity modeling | GENE LOGIC INC. (US) | 2007-03-08 | — | — | US | disclosed |
| US-20070032433-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. | 2007-02-08 | — | — | US | disclosed |
| US-20070032433-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. | 2007-02-08 | — | — | US | disclosed |
| WO-2003062265-A2 | NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |
| US-4889870-A | 2-(2,2-Difluorocyclopropyl)alkyl esters, processes for their preparation and their use as insecticides and acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-12-26 | — | — | US | disclosed |
| EP-0277908-A2 | 2-(2,2-Difluorocyclopropyl)-alkylester, process of preparation and use as insecticide and acaricide | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | HPN, TMPRSS15, VIP | TDP1 3248/4885LMNA 3429/4885F2 569/4885 |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | TDP1 2445/4885LMNA 4173/4885F2 794/4885 |
| US-12312377-B2 | Biconjugatable labels and methods of use | CLTB, HLCS, CD44 | TDP1 815/4885LMNA 1007/4885F2 2935/4885 |
| US-20250059157-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | TDP1 947/4885LMNA 1762/4885F2 4847/4885 |
| US-20070032433-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | HPN, TMPRSS15, VIP | TDP1 3248/4885LMNA 3429/4885F2 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.