Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844269 | 0.93 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1 | |
| SCHEMBL9844330 | 0.92 | OPRL1 (0.54) | SIGMAR1GRM2OPRM1OPRL1OPRD1 | |
| SCHEMBL9844125 | 0.92 | SIGMAR1 (0.61) | SIGMAR1GRM2 | |
| SCHEMBL9678352 | 0.92 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL9844178 | 0.90 | SIGMAR1 (0.58) | SIGMAR1OPRM1OPRL1ALDH1A1OPRD1 | |
| SCHEMBL9844297 | 0.90 | MAOA (0.51) | SIGMAR1GRM2OPRM1OPRL1OPRD1 | |
| SCHEMBL9844429 | 0.90 | OPRL1 (0.58) | SIGMAR1GRM2OPRM1OPRL1OPRD1 | |
| SCHEMBL9844085 | 0.89 | SIGMAR1 (0.68) | SIGMAR1GRM2 | |
| SCHEMBL9844495 | 0.89 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1 | |
| SCHEMBL9844060 | 0.88 | OPRM1 (0.53) | SIGMAR1GRM2OPRM1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |