Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.35 |
| ▸ | PNP | P00491 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002487 | 0.89 | POLB (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL7764760 | 0.89 | POLB (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL2155920 | 0.89 | POLB (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| Hydrochloric Acid SCHEMBL2674244 | 0.87 | POLB (0.48) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL6191432 | 0.84 | ALDH1A1 (0.46) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL7763371 | 0.79 | POLB (0.52) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL7764756 | 0.78 | L3MBTL1 (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL2185067 | 0.78 | L3MBTL1 (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL7764759 | 0.78 | L3MBTL1 (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 | |
| SCHEMBL2185063 | 0.78 | L3MBTL1 (0.50) | POLBL3MBTL1ALDH1A1HRH3SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |