Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844429 | 0.93 | OPRL1 (0.58) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844110 | 0.92 | SIGMAR1 (0.56) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844330 | 0.92 | OPRL1 (0.54) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844063 | 0.91 | SIGMAR1 (0.54) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9677190 | 0.91 | SIGMAR1 (0.68) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844269 | 0.90 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9844297 | 0.88 | MAOA (0.51) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844060 | 0.88 | OPRM1 (0.53) | SIGMAR1ABCB11TP53CYP3A4CYP2D6 | |
| SCHEMBL9844106 | 0.87 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9844178 | 0.87 | SIGMAR1 (0.58) | SIGMAR1OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |