Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677766 | 0.92 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL9844269 | 0.90 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1 | |
| SCHEMBL9844284 | 0.90 | SIGMAR1 (0.54) | SIGMAR1OPRM1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL9844330 | 0.89 | OPRL1 (0.54) | SIGMAR1OPRM1OPRL1OPRD1 | |
| SCHEMBL9844457 | 0.88 | SIGMAR1 (0.64) | SIGMAR1 | |
| SCHEMBL9844328 | 0.88 | OPRL1 (0.51) | SIGMAR1OPRM1OPRL1OPRD1 | |
| SCHEMBL9844297 | 0.87 | MAOA (0.51) | SIGMAR1OPRM1OPRL1OPRD1 | |
| SCHEMBL9844252 | 0.87 | SIGMAR1 (0.56) | SIGMAR1OPRM1OPRL1OPRD1 | |
| SCHEMBL9844429 | 0.87 | OPRL1 (0.58) | SIGMAR1OPRM1OPRL1OPRD1 | |
| SCHEMBL9844110 | 0.86 | SIGMAR1 (0.56) | SIGMAR1OPRM1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |