Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844422 | 0.91 | GRM2 (0.55) | GRM2CARM1PRMT6HTR2ACCR3 | |
| SCHEMBL9676190 | 0.91 | SIGMAR1 (0.59) | GRM2SIGMAR1 | |
| SCHEMBL9844478 | 0.90 | GRM2 (0.60) | GRM2CARM1PRMT6HTR7 | |
| SCHEMBL9844291 | 0.90 | GRM2 (0.55) | GRM2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9844260 | 0.89 | GRM2 (0.54) | GRM2SIGMAR1 | |
| SCHEMBL9844309 | 0.88 | CARM1 (0.45) | GRM2SIGMAR1CARM1PRMT6HTR2A | |
| SCHEMBL9844281 | 0.88 | GRM2 (0.52) | GRM2SIGMAR1CARM1PRMT6HTR2A | |
| SCHEMBL9844088 | 0.88 | GRM2 (0.52) | GRM2SIGMAR1CARM1PRMT6HTR7 | |
| SCHEMBL9844023 | 0.85 | SLC6A2 (0.48) | GRM2SIGMAR1CARM1PRMT6HTR2A | |
| SCHEMBL9844072 | 0.83 | GRM2 (0.53) | GRM2CARM1PRMT6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |