Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678807 | 0.90 | MAOA (0.58) | MAOAMAOBGRM2NOTUMHSD11B1 | |
| SCHEMBL9844499 | 0.90 | HTR2A (0.53) | GRM2KCNH2HTR2AMEN1KMT2A | |
| SCHEMBL9844336 | 0.89 | GRM2 (0.56) | GRM2HSD11B1KCNH2HTR2A | |
| SCHEMBL9844338 | 0.86 | GRM2 (0.51) | GRM2NOTUMHSD11B1KCNH2HTR2A | |
| SCHEMBL9844433 | 0.84 | SIGMAR1 (0.45) | GRM2KCNH2HTR2AKMT2A | |
| SCHEMBL9844055 | 0.83 | GRM2 (0.49) | GRM2KCNH2HTR2AMEN1KMT2A | |
| SCHEMBL9844242 | 0.83 | HTR2A (0.52) | GRM2HTR2A | |
| SCHEMBL9844329 | 0.83 | SIGMAR1 (0.54) | GRM2KCNH2HTR2AMEN1KMT2A | |
| SCHEMBL9844119 | 0.83 | GRM2 (0.56) | MAOAMAOBGRM2HSD11B1 | |
| SCHEMBL9844046 | 0.80 | MAOA (0.57) | MAOAMAOBGRM2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |