Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 5/20 | 0.49 |
| ▸ | ATIC | P31939 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 4/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844836 | 0.95 | DHFR (0.47) | GARTATICDHFR | |
| SCHEMBL9844794 | 0.91 | DHFR (0.51) | GARTATICDHFRTYMS | |
| SCHEMBL9844879 | 0.87 | ATIC (0.48) | GARTATICDHFRTYMS | |
| SCHEMBL9844818 | 0.86 | DHFR (0.54) | GARTATICDHFR | |
| SCHEMBL9844754 | 0.86 | ATIC (0.51) | GARTATICDHFRTYMS | |
| SCHEMBL9844885 | 0.86 | ATIC (0.51) | GARTATICDHFRTYMS | |
| SCHEMBL9844789 | 0.82 | GART (0.48) | GARTATICDHFRTYMS | |
| SCHEMBL9844814 | 0.81 | DHFR (0.52) | GARTATICDHFRTYMS | |
| SCHEMBL9844804 | 0.75 | GART (0.56) | GARTATICDHFR | |
| SCHEMBL9844819 | 0.73 | DHFR (0.51) | GARTATICDHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | claimed |
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |