Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844745 | 0.90 | MAPT (0.35) | NPC1RAB9AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2072670 | 0.86 | DRD2 (0.40) | NPC1RAB9AALDH1A1DRD2PTPN1 | |
| SCHEMBL1386593 | 0.86 | DRD2 (0.40) | NPC1RAB9AALDH1A1DRD2PTPN1 | |
| SCHEMBL9844937 | 0.72 | PTPN1 (0.41) | NPC1RAB9AALDH1A1TSHRPTPN1 | |
| SCHEMBL9844938 | 0.72 | PTPN1 (0.41) | NPC1RAB9AALDH1A1TSHRPTPN1 | |
| SCHEMBL8997195 | 0.66 | ATIC (0.35) | MAPTKMT2ATP53MEN1TLR7 | |
| SCHEMBL71401 | 0.63 | PTPN1 (0.73) | NPC1RAB9AALDH1A1TSHRPTPN1 | |
| SCHEMBL5379059 | 0.63 | PTPN1 (0.73) | NPC1RAB9AALDH1A1TSHRPTPN1 | |
| SCHEMBL71402 | 0.63 | PTPN1 (0.73) | NPC1RAB9AALDH1A1TSHRPTPN1 | |
| SCHEMBL2627847 | 0.63 | PTPN1 (0.73) | NPC1RAB9AALDH1A1TSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |