Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.88 |
| ▸ | HTR7 | P34969 | 5/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844858 | 0.94 | HTR1A (1.00) | HTR1AHTR7ADRA1BDRD2ADRA1A | |
| SCHEMBL10521533 | 0.86 | HTR1A (0.72) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10566798 | 0.85 | HTR1A (0.71) | HTR1AHTR7 | |
| SCHEMBL7668123 | 0.84 | HTR7 (0.95) | HTR1AHTR7DRD2DRD5DRD3 | |
| SCHEMBL6865196 | 0.83 | HTR7 (0.87) | HTR1AHTR7DRD2DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL6866824 | 0.83 | HTR7 (0.93) | HTR1AHTR7DRD2DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL7663753 | 0.82 | HTR7 (0.85) | HTR1AHTR7DRD2DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL9545425 | 0.81 | HTR1A (0.64) | HTR1AHTR7ADRA1BDRD2DRD3 | |
| SCHEMBL21802017 | 0.79 | HTR7 (0.76) | HTR1AHTR7ADRA1BDRD2DRD5 | |
| SCHEMBL11465528 | 0.79 | SIGMAR1 (0.76) | HTR1AHTR7DRD2DRD3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447345-A2 | New Azaspyro [4.5] decane-7,9-dione derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1991-09-18 | — | — | EP | claimed |
| EP-0447345-A2 | New Azaspyro [4.5] decane-7,9-dione derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1991-09-18 | — | — | EP | disclosed |