Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248149 | 0.78 | NMT1 (0.50) | ACHEKMT2AGLASMN1; SMN2TSHR | |
| SCHEMBL2910532 | 0.76 | POLB (0.62) | POLBHTTACHEKMT2AKDM4E | |
| SCHEMBL7285425 | 0.76 | PTGDR2 (0.43) | TSHRAPEX1TDP1 | |
| SCHEMBL15642113 | 0.74 | POLB (0.65) | POLBHTTACHEKMT2AKDM4E | |
| SCHEMBL2912166 | 0.74 | POLB (0.56) | POLBHTTACHEKMT2AKDM4E | |
| SCHEMBL3268680 | 0.74 | POLB (0.51) | POLBHTTACHEKMT2AKDM4E | |
| SCHEMBL7313649 | 0.73 | RAPGEF4 (0.38) | HTTKMT2AKDM4EGAAMAPT | |
| SCHEMBL16666424 | 0.73 | POLB (0.58) | POLBHTTACHEKMT2AKDM4E | |
| SCHEMBL2263745 | 0.72 | RAPGEF4 (0.40) | HTTKMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL15867097 | 0.72 | ACHE (0.57) | POLBHTTACHEKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413839-A1 | GHRH analogs | The Administrators of The Tulane Educational Fund (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4914189-A | STIMULATES RELEASE OF GROWTH HORMONE | THE ADMINSTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1990-04-03 | — | — | US | disclosed |