SCHEMBL7313649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2263745	0.90	RAPGEF4 (0.40)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL1021882	0.85	KMT2A (0.44)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL996488	0.79	KMT2A (0.38)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL248149	0.79	NMT1 (0.50)	RAPGEF4KMT2AMEN1TSHRSMN1; SMN2
	SCHEMBL6557356	0.79	RAPGEF4 (0.33)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL10190122	0.78	MAPK1 (0.47)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL83875	0.76	LMNA (0.39)	RAPGEF4KMT2AMEN1MAPK1LMNA
	SCHEMBL2932203	0.76	RAB9A (0.53)	RAPGEF4KMT2AMEN1MAPK1LMNA
	2-Mercaptoethanol SCHEMBL6558446	0.76	ALDH1A1 (0.33)	RAPGEF4MAPK1LMNAGAAHTT
	SCHEMBL6557490	0.76	CA12 (0.35)	RAPGEF4KMT2AMEN1MAPK1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.