Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308863 | 0.93 | PPARG (0.46) | ACHEESR2PPARGFFAR1AKR1B1 | |
| SCHEMBL9308844 | 0.85 | PPARG (0.45) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL9846039 | 0.85 | PPARG (0.45) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL9846092 | 0.84 | PPARG (0.45) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL9846024 | 0.84 | PPARG (0.47) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL9846033 | 0.83 | PPARG (0.43) | ACHEESR2PPARGAGTR1APLNR | |
| SCHEMBL7315508 | 0.82 | ESR2 (0.42) | ESR2PPARGFFAR1AKR1B1ALDH1A1 | |
| SCHEMBL9310919 | 0.81 | PPARG (0.47) | ACHEESR2PPARGAGTR1FFAR1 | |
| SCHEMBL8979828 | 0.80 | ACHE (0.46) | ACHEPPARGAGTR1 | |
| SCHEMBL9308992 | 0.79 | CYP1A2 (0.45) | ACHEESR2PPARGFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |