Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308863 | 0.85 | PPARG (0.46) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL9308512 | 0.84 | PPARG (0.45) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL9308565 | 0.84 | PPARG (0.45) | PPARG | |
| SCHEMBL9310919 | 0.84 | PPARG (0.47) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL9308516 | 0.84 | PPARG (0.44) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL9308652 | 0.82 | PPARG (0.43) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL7312142 | 0.80 | PPARG (0.46) | PPARGACHEFFAR1AKR1B1ESR2 | |
| SCHEMBL9308911 | 0.79 | PPARG (0.41) | ALDH1A1PPARGKDM4EHPGDACHE | |
| SCHEMBL9846002 | 0.79 | ACHE (0.43) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL9250489 | 0.79 | PPARG (0.43) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |